In bipolar disorder, people experience abnormally
elevated (manic or hypomanic) mood states which interfere with the functions of
ordinary life. Many people with bipolar disorder also experience periods of
depressed mood, but this is not universal. There is no simple physiological
test to confirm the disorder. Diagnosing bipolar disorder is often difficult,
even for mental health professionals. In particular, it can be difficult to
distinguish depression caused by bipolar disorder from pure unipolar depression.
The younger the age of onset, the more likely the
first few episodes are to be depressive. Because a bipolar diagnosis
requires a manic or hypomanic episode, many patients are initially diagnosed
and treated as having major depression.
Manic
episodes
Mania is the defining feature of bipolar disorder.
Mania is a distinct period of elevated or irritable mood, which can take the
form of euphoria, and lasts for at least a week (less if hospitalization is
required). People with mania commonly experience an increase in energy and a
decreased need for sleep, with many often getting as little as three or four
hours of sleep per night. Some can go days without sleeping. A manic person may
exhibit pressured speech, with thoughts experienced as
racing Attention span is low, and a person in a manic state may be
easily distracted. Judgment may be impaired, and sufferers may go on spending
sprees or engage in risky behavior that is not normal for them. They may
indulge in substance abuse, particularly alcohol or other depressants, cocaine
or other stimulants, or sleeping pills. Their behavior may become aggressive,
intolerant, or intrusive. They may feel out of control or unstoppable, or as if
they have been "chosen" and are "on a special mission", or
have other grandiose or delusional ideas. Sexual drive may increase. At more
extreme levels, a person in a manic state can experience psychosis, or a break with reality, where
thinking is affected along with mood. This can occasionally lead to violent
behaviors. Some people in a manic state experience severe anxiety and are irritable (to the
point of rage), while others areeuphoric and
grandiose. The severity of manic symptoms can be measured by rating scales such
as the Altman
Self-Rating Mania Scale and clinician-based Young Mania
Rating Scale.
The onset of a manic episode is often foreshadowed
by sleep disturbances. Mood changes, psychomotor and
appetite changes, and an increase in anxiety can also occur up to three weeks before
a manic episode develops.
Hypomanic
episodes
Hypomania is a
mild to moderate level of elevated mood, characterized by optimism, pressure of
speech and activity, and decreased need for sleep. Generally, hypomania does
not inhibit functioning as mania does. Many people with hypomania are
actually more productive than usual, while manic individuals have difficulty
completing tasks due to a shortened attention span. Some hypomanic people show
increased creativity, although others demonstrate poor judgment and irritability.
Many experience hypersexuality.
Hypomanic people generally have increased energy and increased activity levels.
They do not, however, have delusions or
hallucinations.
Hypomania may feel good to the person who
experiences it. Thus, even when family and friends recognize mood swings, the
individual often will deny that anything is wrong. What might be called a
"hypomanic event", if not accompanied by depressive episodes, is
often not deemed as problematic, unless the mood changes are uncontrollable,
volatile or mercurial. If left untreated, an episode of hypomania can last
anywhere from a few days to several years. Most commonly, symptoms continue for
a few weeks to a few months.
Depressive
episodes
Signs and symptoms of the depressive
phase of bipolar disorder include persistent feelings of sadness, anxiety, guilt, anger, isolation, or hopelessness; disturbances in sleep and
appetite; fatigue and loss of interest in usually enjoyable activities;
problems concentrating; loneliness, self-loathing, apathy or indifference; depersonalization; loss of interest in
sexual activity; shyness or social anxiety; irritability, chronic pain
(with or without a known cause); lack of motivation; and morbid suicidal
thoughts. In severe cases, the individual may become psychotic, a condition also known as severe
bipolar depression with psychotic features. These symptoms include delusions or, less commonly, hallucinations, usually unpleasant. A major
depressive episode persists for at least two weeks, and may continue for over
six months if left untreated.
Mixed
affective episodes
In the context of bipolar disorder, a mixed state is
a condition during which symptoms of mania and depression occur simultaneously.
Typical examples include weeping during a manic episode or racing thoughts
during a depressive episode. Individuals may also feel very frustrated in this
state, for example thinking grandiose thoughts while at the same time feeling
like a failure. Mixed states are often the most dangerous period of mood
disorders, during which the risks of substance abuse, panic disorder, suicide attempts, and other
complications increase greatly.
Associated
features
Associated features are clinical phenomena that
often accompany the disorder but are not part of the diagnostic criteria. In
adults with the condition, bipolar disorder is often accompanied by changes in cognitive processes and abilities.
These include reduced attentional and executive capabilities
and impaired memory. How the individual processes the
world also depends on the phase of the disorder, with differential
characteristics between the manic, hypomanic and depressive states. Some
studies have found a significant association between bipolar disorder and creativity. Some patients may have
difficulty in maintaining relationships.
There are several common childhood precursors seen
in children who later receive a diagnosis of bipolar disorder. These include
mood abnormalities, full major depressive episodes, and ADHD.
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